Gut Health Supplements [That Actually Work In 2023]

Gut health plays a crucial role in our overall well-being, impacting everything from digestion to immunity, and even our mental health. In an increasingly busy world, maintaining our gut’s delicate balance of beneficial bacteria is essential for optimal wellness.

One way to support this balance is through the use of targeted gut health supplements.

If you’re looking to improve your gut health, you may be considering taking supplements. They can help promote the growth of beneficial bacteria in your digestive tract, which can lead to better digestion, improved immune function, and even a better mood. However, with so many options on the market, it can be challenging to determine which supplements are right for you.

In this article, we will explore the various types of supplements available, their potential benefits on your body and mind, and tips for choosing the best options for your needs.

Understanding The Importance Of Gut Health

The gut microbiome plays a critical role in maintaining overall health, as it is responsible for digesting food, absorbing nutrients, and regulating the immune system, among other things.

What is The Gut Microbiome?

The gut microbiome refers to the diverse community of trillions of microorganisms, primarily bacteria, that reside in our digestive system.

A healthy gut microbiome is teeming with a rich variety of beneficial bacteria that work harmoniously to crowd out harmful pathogens and maintain balance within the ecosystem.

gut microbiome

For example, lactobacillus acidophilus helps reduce inflammation while bacillus subtilis promotes good digestion and supports immune health.

Including fermented foods like yogurt or kimchi in your diet can support your gut’s microbial diversity while certain prebiotic-rich foods like onions, garlic, bananas, and legumes fuel these friendly microbes for better growth.

How a Healthy Gut Affects Overall Health

A healthy gut is crucial to maintaining overall health and well-being, acting as the foundation for numerous bodily functions.

A healthy gut means a healthy digestive system, which is responsible for breaking down your food into the nutrients your body needs to function properly. The digestive system includes the stomach, small intestine, large intestine, and colon. When your gut is healthy, it can better absorb nutrients, remove waste, and fight off harmful bacteria.

A thriving microflora population aids absorption of vitamins and minerals which are vital components for boosting energy levels and general wellness.

A healthy gut also plays a significant role in your immune system. The gut is home to trillions of bacteria that help keep your immune system functioning correctly.

Good gut health also impacts mental and skin health.

Speaking of mental health the gut and brain are connected through the gut-brain axis, which means that the health of your gut can impact your mood, stress levels, and even your sleep.

And as for the skin, the gut microbiome manages inflammation — a common culprit behind various skin problems such as acne or eczema as well as rheumatoid arthritis.

Types of Gut Health Supplements

Sometimes it can be challenging to get all the nutrients and prebiotics you need from food alone. This is where gut health supplements can come in handy.

Gut Health Supplements

These supplements balance the bacteria in your gut, improve your digestion, and boost your immune system.

Some of the most common gut health supplements include probiotics, prebiotics, fiber, collagen, zinc, and licorice root.

Fiber is an important nutrient that can help regulate your bowel movements, reduce inflammation, and lower your risk of developing certain diseases.

Collagen is a protein that can help support your gut lining and improve your digestion.

Zinc is a mineral that can help boost your immune system and support your gut health. Licorice root is an herb that can help reduce inflammation and improve your digestion.

It’s important to note that not all supplements are created equal, and some may even be harmful to some people. Therefore, do your research and talk to your healthcare provider before starting any new supplement regimen.

With that out of the way, let’s take a closer look at probiotics, prebiotics, digestive enzymes, fiber supplements, and omega-3 supplements as some of the supplements available.


Probiotics comprising live bacteria and yeast have gained considerable attention in recent years due to their numerous benefits for gut health.

These beneficial microorganisms restore the natural balance of good gut bacteria, which can be disrupted due to factors like poor diet, stress, or antibiotic use.

One fascinating example of probiotics’ effectiveness is how they strengthen our immune system.

Moreover, certain strains like Lactobacillus acidophilus have shown promise in treating symptoms associated with irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD).

Some of the best probiotic supplements include:

  • Garden of Life Dr. Formulated Probiotics
  • Align Probiotic
  • Culturelle Daily Probiotic
  • Renew Life Ultimate Flora Probiotic
  • Fermented foods like sauerkraut, kimchi, and kefir are also great sources of healthy bacteria. These foods contain natural probiotics that can help support your gut microbiome.

Look for a supplement that contains a high number of colony-forming units (CFUs). This is a measure of the number of live bacteria in the supplement. The higher the CFU count, the more effective the supplement is likely to be.

In addition to a high CFU count, choose a probiotic supplement that contains strains of bacteria that are effective for the specific gut health issue you’re trying to address.

For example, if you’re looking to improve your digestion, look for a supplement that contains strains of bacteria that are known to aid in digestion.


Prebiotics are a type of dietary fiber that feed the good bacteria in your gut. Unlike probiotics, which introduce new bacteria to your system, prebiotics nourish the beneficial microbes already present in your digestive tract.


Some examples of prebiotic foods include onions, garlic, asparagus, bananas, and legumes. Incorporating these foods into your diet can play an important role in maintaining a healthy balance of gut flora.

Some prebiotic supplements include PrebioThriveTransparent Labs Prebiotic Greens, and Green Vibrance.

Also look for supplements that contain natural sources of prebiotic fiber, such as chicory root, inulin, slippery elm, and psyllium. They can also contain fructooligosaccharides (FOS), and galactooligosaccharides (GOS).

Digestive Health Supplements

Digestive health supplements typically contain digestive enzymes. Digestive enzymes are proteins that our bodies naturally produce to break down food into smaller molecules for easier absorption. However, sometimes our bodies may not produce enough digestive enzymes, leading to digestion issues such as gas, bloating, and stomach discomfort.

This is where digestive enzyme supplements come in handy.

Some common types of digestive enzymes include amylase which breaks down carbohydrates, protease for protein breakdown, and lipase for the digestion of fats.

Fiber Supplements

Since fiber promotes good digestive health, fiber supplements or supplements with fiber like Iaso Tea and Valentus can be a great addition to your diet for optimal gut health.

These supplements provide your body with the necessary amounts of fiber that you may not be getting from your regular diet, helping to promote regular bowel movements and prevent constipation.

In addition, fiber supplements can help reduce inflammation in the gut by feeding beneficial bacteria in the colon. Some examples of high-fiber foods include oats, flax seeds, chia seeds, whole grains, and fruits like raspberries and blackberries.

Omega-3 Supplements

Omega-3 supplements contain Omega-3 fatty acids which are essential fats that your body needs but cannot produce on its own. They are found in fatty fish like salmon, mackerel, and sardines.

Omega-3 Supplements

These supplements contain essential fatty acids, such as EPA and DHA, which are crucial for maintaining healthy cell membranes and supporting proper brain function.

In addition to benefiting the brain and heart, omega-3s have also been shown to reduce inflammation in the body, which can benefit those with inflammatory bowel disease or other digestive issues.

Omega-3 supplements can be found in various forms including fish oil capsules or vegan alternatives like flaxseed oil or algae-based supplements.


Magnesium is a mineral that is essential for your body’s function. It can help improve your sleep quality and reduce symptoms of anxiety and depression.

Some studies have also shown that magnesium can help reduce inflammation in your body. Look for magnesium supplements that contain magnesium citrate, magnesium glycinate, or magnesium oxide.

Vitamin D

Vitamin D is a vitamin that your body needs to absorb calcium and maintain strong bones. It is also important for your immune system and brain function.

Some studies have shown that low levels of vitamin D are associated with an increased risk of depression. Look for vitamin D supplements that contain vitamin D3.

Supplements for Immune Health

Restore is a liquid supplement that contains minerals and amino acids that can help strengthen the tight junctions in your gut lining. This can help prevent toxins and other harmful substances from leaking into your bloodstream, which can compromise your immune system.

Restore Supplement

In addition to Restore, there are a few other gut health supplements that can support immune health. These include:

  • Vitamin D: Vitamin D is essential for immune health, and many people are deficient in this important nutrient. Taking a vitamin D supplement can help support your immune system and protect against illness.
  • Zinc: Zinc is another nutrient that is important for immune health. It plays a role in the development and function of immune cells, and taking a zinc supplement can help support a healthy immune system.
  • Elderberry: Elderberry is a fruit that has been shown to have immune-boosting properties. Taking an elderberry supplement can help support your immune system and protect against illness.

By adding these gut health supplements to your daily regimen, you can help support your immune system and protect yourself against illness. As always, be sure to talk to your doctor before starting any new supplement regimen.

Supplements for Digestive Health

In addition to probiotics and digestive enzymes, there are a variety of other digestive health supplements that may help promote healthy digestion and reduce inflammation. These include:

  • Licorice root: This supplement has been shown to have anti-inflammatory properties and may help reduce inflammation in the digestive system.Licorice Root
  • Turmeric: This spice has anti-inflammatory properties and may help reduce inflammation in the gut.
  • Fiber supplements: Fiber can help promote healthy digestion and reduce constipation.
  • Omega-3 fatty acids: These healthy fats have anti-inflammatory properties and may help reduce inflammation in the digestive system.

If you suffer from digestive issues such as inflammatory bowel disease or ulcerative colitis, talk to your doctor before taking any supplements to determine which supplements may be helpful for your specific condition and how to safely incorporate them into your diet.

If you’re experiencing symptoms such as abdominal pain, bloating, or diarrhea, talk to your doctor to determine the underlying cause and develop an appropriate treatment plan.

Benefits of Gut Health Supplements

Gut health supplements offer a variety of benefits such as:

Improved Digestion

Consuming these supplements can improve digestion by bringing balance to the gut microbiome. The good bacteria found in probiotics help break down food while digestible fiber promotes regular bowel movements.

Digestive enzymes can also aid in breaking down food, especially for those with lactose intolerance or difficulty digesting protein-rich foods.

A healthy digestive system not only reduces bloating and discomfort but also absorbs essential nutrients from our diet, leading to overall improved wellness.

Research suggests that a nutrient-dense diet along with supplements can positively impact general digestive health, treating symptoms such as abdominal pain and antibiotic-associated diarrhea.

Boosted Immunity

A significant portion of the immune system is found within the gut, meaning that a healthy digestive tract is essential to our overall well-being. Gut health supplements can play an important role in boosting immunity.

Probiotics, prebiotics, and fiber supplements can help support immune health by promoting a healthy balance of bacteria in the gut. A good mix of beneficial bacteria can increase resistance to harmful germs and alleviate inflammation, which contributes to more effective immune function.

Some bacteria in the gut help control how immune cells function. Therefore, when your microbiome isn’t healthy, the immune system becomes too active, which can be damaging.

That’s why you include fiber in your prebiotics because the by-products of fiber being broken down tell the immune system to stay calm.

Manage Your Weight

How much and what you eat impact your weight, but there’s more to it than the number of calories.

The bacteria in your gut help break down fat, extract calories from food, and influence the production of appetite-regulating hormones like leptin and ghrelin.

If there is an imbalance between good and bad bacteria, your digestive system might not perform those functions as well as it should.

On top of that, research shows that obese people have a different microbiome compared to those who are lean suggesting that those who have weight problems are not as attuned to processing food as their leaner counterparts.

Better Skin Health

A healthy microbiome can help to regulate the bacteria in your skin and alleviate common skin problems.

When you have an imbalance in your gut microbiome, you can suffer inflammation that affects the entire body, including your skin, causing breakouts.

A study found that 54 percent of patients with acne had unhealthy microbiomes.

Some people have treated skin conditions like eczema or acne with skin-care products that contain probiotic extracts and prebiotics.

Reduced Inflammation

Gut health supplements can also help reduce inflammation in the body. Chronic inflammation is linked to several diseases, such as arthritis, so you want to keep inflammation levels under control.

Studies have shown that probiotics and prebiotics can lower certain markers of inflammation in the body, such as C-reactive protein (CRP). Additionally, fiber supplements can promote the growth of beneficial bacteria in the gut and reduce harmful bacteria.

This shift towards a healthier microbial balance can lead to reduced inflammation throughout the body.

Enhanced Nutrient Absorption

Taking supplements for gut health can enhance nutrient absorption. When the digestive system is functioning well, it can break down food and absorb nutrients easily. This means that your body will receive more of the vitamins and minerals it needs to function properly.

On the other hand, when there are issues with digestion or inflammation in the gut, nutrient absorption can be compromised. Supplements like digestive enzymes can help improve nutrient breakdown and make it easier for your body to absorb what it needs from food.

Better Mental Health

Good gut health can be linked to better mental health. Research has shown that there is a connection between the gut and the brain, known as the gut-brain axis.

The enteric nervous system is a complex network with over 100 million nerve endings that lines your gastrointestinal tract. It connects your gut to your brain.

Research has shown links between changes in your microbiome to depression and anxiety.

A study published in the Journal of Psychiatric Research found that participants who took probiotics had reduced symptoms of depression compared to those who did not take probiotics.

Another research study suggests that certain strains of bacteria in the gut can produce neurotransmitters such as serotonin, which can regulate anxiety and mood disorders. In addition to probiotics, prebiotics have also been shown to improve cognition and decrease stress levels.

How To Choose The Right Gut Health Supplement

To ensure you choose the right gut health supplement, take these steps:

Consult With a Healthcare Professional

Before starting any new supplement regimen for gut health, consult with a healthcare professional. This is especially true if you have underlying health conditions or are taking medications that could interact with certain supplements.

Additionally, consulting with a healthcare professional can ensure that the supplements you choose are safe and of high quality. They may also be able to recommend specific brands or types of supplements based on their experience and knowledge.

Check Quality Certifications

When selecting gut health supplements, check for quality certifications as these indicate that the product has been thoroughly tested and meets certain standards.

Look for certifications such as GMP (Good Manufacturing Practice) or NSF (National Sanitation Foundation), which ensure that the supplement has been produced in a safe and controlled environment.

It’s also helpful to research the brand and read reviews from other consumers to ensure their products are trustworthy. Additionally, be wary of any claims made by supplement companies that sound too good to be true – there is no one “miracle cure” for gut health, so approach any wild claims with skepticism.

Read Labels and Do Research

Make sure to look for quality certifications that ensure the product has been independently tested for potency and purity.

It’s also important to know which strains of beneficial bacteria are included in the supplement as different strains can have varying effects on gut health.

By taking the time to carefully evaluate dietary supplements before purchasing them, you can improve your chances of finding a high-quality product that supports your overall digestive and immune function.

Consider Your Needs & Preferences

One factor to consider is any specific digestive issues or conditions you may have, such as irritable bowel syndrome or inflammatory bowel disease.

For example, if you struggle with such diseases, certain probiotic strains may be more effective in treating symptoms than others.

Another consideration is personal preference in terms of supplement form, whether that be capsules, powders, or liquids.

Frequently Asked Questions

What are probiotics?

Probiotics are live bacteria and yeasts that are good for your health, especially your digestive system. They are often referred to as “good” or “friendly” bacteria because they help keep your gut healthy. Probiotics can be found in some foods, such as yogurt and kefir, and in dietary supplements.

How do gut health supplements work?

They work by providing your body with nutrients that support the growth of good bacteria in your gut. They can also help reduce inflammation and improve the overall health of your digestive system. The exact way that gut health supplements work can vary depending on the specific supplement you are taking.

What are some natural ways to improve gut health?

In addition to taking gut health supplements, there are several natural ways to improve your gut health. These include eating a healthy diet that is rich in fiber, staying hydrated, getting regular exercise, reducing stress, and getting enough sleep.

Are there any side effects to taking gut health supplements?

While most gut health supplements are generally safe, some people may experience mild side effects such as bloating, gas, or diarrhea. If you experience any unusual symptoms after taking a gut health supplement, it’s important to speak with your healthcare provider.

Can gut health supplements help with weight loss?

While some gut health supplements may claim to help with weight loss, there is limited scientific evidence to support these claims. It’s important to remember that taking supplements alone is not a substitute for healthy eating and exercise.

Do gut health supplements help with digestive issues?

Gut health supplements may be helpful for some digestive issues, such as irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD). However, it’s important to speak with your healthcare provider before taking any supplements to ensure that they are safe and appropriate for your specific health needs.


Taking gut health supplements can be a great way to support your digestive system and overall health. However, it is important to remember that supplements should not be used as a substitute for a healthy diet and lifestyle.

When choosing a gut health supplement, make sure to do your research and choose a high-quality product from a reputable brand. Look for supplements that contain probiotics, prebiotics, and other beneficial ingredients like digestive enzymes and fiber.

It is also important to follow the recommended dosage and consult with your healthcare provider before starting any new supplement regimen. They can help you determine if a supplement is right for you and ensure that it does not interact with any medications you may be taking.

In addition to taking supplements, there are other steps you can take to support your gut health. Eating a balanced diet that is rich in fiber and fermented foods, staying hydrated, and managing stress can all help promote a healthy gut microbiome.

Remember, everyone’s digestive system is unique, so what works for one person may not work for another. It may take some trial and error to find the right supplement and lifestyle habits that work best for you. But with patience and persistence, you can support your gut health and overall well-being.